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1

Autism-Misregulated eIF4G Microexons Control Synaptic Translation and Higher Order Cognitive Functions

Gonatopoulos-Pournatzis, Thomas, Niibori, Rieko, Salter, Eric W., Weatheritt, Robert J., Tsang, Brian, Farhangmehr, Shaghayegh, Liang, Xinyi, Braunschweig, Ulrich, Roth, Jonathan, Zhang, Shen, Henders

Journal:

Year:

2020

Language:

english

File:

PDF, 3.94 MB

english, 2020

2

RAM/Fam103a1 Is Required for mRNA Cap Methylation

Thomas Gonatopoulos-Pournatzis, Sianadh Dunn, Rebecca Bounds, Victoria H. Cowling

Journal:

Year:

2011

Language:

english

File:

PDF, 999 KB

english, 2011

3

Widespread intron retention in mammals functionally tunes transcriptomes

Braunschweig, Ulrich, Barbosa-Morais, Nuno L., Pan, Qun, Nachman, Emil N., Alipanahi, Babak, Gonatopoulos-Pournatzis, Thomas, Frey, Brendan, Irimia, Manuel, Blencowe, Benjamin J.

Journal:

Genome Research

Year:

2014

Language:

english

File:

PDF, 1.77 MB

english, 2014

4

A Highly Conserved Program of Neuronal Microexons Is Misregulated in Autistic Brains

Irimia, Manuel, Weatheritt, Robert J., Ellis, Jonathan D., Parikshak, Neelroop N., Gonatopoulos-Pournatzis, Thomas, Babor, Mariana, Quesnel-Vallières, Mathieu, Tapial, Javier, Raj, Bushra, O’Hanlon, D

Journal:

Year:

2014

Language:

english

File:

PDF, 1.42 MB

english, 2014

5

S-Adenosyl Homocysteine Hydrolase Is Required for Myc-Induced mRNA Cap Methylation, Protein Synthesis, and Cell Proliferation

Fernandez-Sanchez, M. E., Gonatopoulos-Pournatzis, T., Preston, G., Lawlor, M. A., Cowling, V. H.

Journal:

Molecular and Cellular Biology

Year:

2009

Language:

english

File:

PDF, 1.92 MB

english, 2009

6

An alternative splicing event amplifies evolutionary differences between vertebrates

Gueroussov, S., Gonatopoulos-Pournatzis, T., Irimia, M., Raj, B., Lin, Z.-Y., Gingras, A.-C., Blencowe, B. J.

Journal:

Year:

2015

Language:

english

File:

PDF, 868 KB

english, 2015

7

Cap-binding complex (CBC)

Gonatopoulos-Pournatzis, T., Cowling, V.H.

Journal:

Biochemical Journal

Year:

2014

File:

PDF, 23 KB

2014

8

mRNA Cap Methylation in Pluripotency and Differentiation

Grasso, Laura, Suska, Olga, Davidson, Lindsay, Gonatopoulos-Pournatzis, Thomas, Williamson, Ritchie, Wasmus, Lize, Wiedlich, Simone, Peggie, Mark, Stavridis, Marios P., Cowling, Victoria H.

Journal:

Year:

2016

Language:

english

File:

PDF, 3.76 MB

english, 2016

9

Control of embryonic stem cell self-renewal and differentiation via coordinated alternative splicing and translation of YY2

Tahmasebi, Soroush, Jafarnejad, Seyed Mehdi, Tam, Ingrid S., Gonatopoulos-Pournatzis, Thomas, Matta-Camacho, Edna, Tsukumo, Yoshinori, Yanagiya, Akiko, Li, Wencheng, Atlasi, Yaser, Caron, Maxime, Brau

Journal:

Proceedings of the National Academy of Sciences

Year:

2016

Language:

english

File:

PDF, 1.26 MB

english, 2016

10

Misregulation of an Activity-Dependent Splicing Network as a Common Mechanism Underlying Autism Spectrum Disorders

Quesnel-Vallières, Mathieu, Dargaei, Zahra, Irimia, Manuel, Gonatopoulos-Pournatzis, Thomas, Ip, Joanna Y., Wu, Mingkun, Sterne-Weiler, Timothy, Nakagawa, Shinichi, Woodin, Melanie A., Blencowe, Benja

Journal:

Year:

2016

Language:

english

File:

PDF, 2.45 MB

english, 2016

11

Multilayered Control of Alternative Splicing Regulatory Networks by Transcription Factors

Han, Hong, Braunschweig, Ulrich, Gonatopoulos-Pournatzis, Thomas, Weatheritt, Robert J., Hirsch, Calley L., Ha, Kevin C.H., Radovani, Ernest, Nabeel-Shah, Syed, Sterne-Weiler, Tim, Wang, Juli, O’Hanlo

Journal:

Year:

2017

Language:

english

File:

PDF, 3.05 MB

english, 2017

12

Genome-wide CRISPR-Cas9 Interrogation of Splicing Networks Reveals a Mechanism for Recognition of Autism-Misregulated Neuronal Microexons

Gonatopoulos-Pournatzis, Thomas, Wu, Mingkun, Braunschweig, Ulrich, Roth, Jonathan, Han, Hong, Best, Andrew J., Raj, Bushra, Aregger, Michael, O’Hanlon, Dave, Ellis, Jonathan D., Calarco, John A., Mof

Journal:

Year:

2018

Language:

english

File:

PDF, 4.92 MB

english, 2018

13

Mechanisms of Neuronal Alternative Splicing and Strategies for Therapeutic Interventions

Lopez Soto, Eduardo Javier, Gandal, Michael J., Gonatopoulos-Pournatzis, Thomas, Heller, Elizabeth A., Luo, Diou, Zheng, Sika

Journal:

Journal of Neuroscience

Year:

2019

File:

PDF, 400 KB

2019

14

Genetic interaction mapping and exon-resolution functional genomics with a hybrid Cas9âCas12a platform

Gonatopoulos-Pournatzis, Thomas, Aregger, Michael, Brown, Kevin R., Farhangmehr, Shaghayegh, Braunschweig, Ulrich, Ward, Henry N., Ha, Kevin C. H., Weiss, Alexander, Billmann, Maximilian, Durbic, Tanj

Journal:

Nature Biotechnology

Year:

2020

Language:

english

File:

PDF, 3.81 MB

english, 2020

15

Microexons: at the nexus of nervous system development, behaviour and autism spectrum disorder

Gonatopoulos-Pournatzis, Thomas, Blencowe, Benjamin J

Journal:

Current Opinion in Genetics & Development

Year:

2020

File:

PDF, 1.89 MB

2020